Reduced Loa loa microfilaria count ten to twelve months after a single dose of ivermectin
| Autor: | Alain Ferrer, Dominique Richard-Lenoble, Maryvonne Kombila, Thanh Hai Duong, P. Gaxotte, P. Bureau |
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| Rok vydání: | 1997 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Helminthiasis Gastroenterology Microfilaria Single dose regimen Loa Loiasis Ivermectin Internal medicine parasitic diseases medicine Animals Humans Gabon Anthelmintic Microfilariae Aged integumentary system biology business.industry Antinematodal Agents Public Health Environmental and Occupational Health General Medicine Middle Aged biology.organism_classification medicine.disease Peripheral blood Surgery Infectious Diseases Female Parasitology business Loa loa After treatment Follow-Up Studies medicine.drug |
| Zdroj: | Transactions of the Royal Society of Tropical Medicine and Hygiene. 91:592-593 |
| ISSN: | 0035-9203 |
| DOI: | 10.1016/s0035-9203(97)90040-7 |
| Popis: | The action of a single dose of ivermectin (200 micrograms/kg) on 71 Gabonese patients with Loa loa microfilariae in the peripheral blood, and living in areas highly endemic for loiasis, has been evaluated. Ten to 12 months after treatment, 43 patients (63%) had no circulating microfilaria and the geometric mean peripheral blood microfilaria count had decreased by 88.6% (P0.02). Thus, a single annual dose of ivermectin can markedly reduce loiasis transmission. |
| Databáze: | OpenAIRE |
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