Cryocrystalglobulinemia as a cause of systemic vasculopathy and widespread erosive arthropathy
| Autor: | Barbara Bucki, T. Papo, P. Godeau, Christian Jorgensen, Thomas Bardin, C de Gennes, Elisabeth Dion, A Quillard, Jacques Sany, J.C. Piette, Lucile Musset |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Systemic disease
Pathology medicine.medical_specialty Immunology Paraproteinemias Inflammation Hypertension Malignant Pathogenesis Cryoglobulin Rheumatology Arthropathy medicine Humans Immunology and Allergy Pharmacology (medical) Vascular Diseases Arthrography Cryoglobulins Purpura business.industry Vascular disease Middle Aged medicine.disease Cryoglobulinemia Female Joint Diseases medicine.symptom Crystallization business Vasculitis |
| Zdroj: | Arthritis & Rheumatism. 39:335-340 |
| ISSN: | 1529-0131 0004-3591 |
| DOI: | 10.1002/art.1780390225 |
| Popis: | This report describes the case of woman who was admitted to the hospital for highly destructive axial and peripheral arthropathy in association with acute malignant hypertension and skin purpura. Type I IgGkappa serum cryoglobulinemia was identified and was classified as a monoclonal gammopathy of unknown significance. Cryoglobulin was shown to crystallize in the serum and synovium fluid and was responsible for both granulomatous microcrystalline synovial inflammation and occlusive vasculopathy in the kidneys and skin. Cryocrystalglobulinemia pathogenicity and therapeutic implications are discussed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text