Ring-Like Enhancement of Hepatocellular Carcinoma in Gadoxetic Acid–Enhanced Multiphasic Hepatic Arterial Phase Imaging With Differential Subsampling With Cartesian Ordering
Autor: | Shintaro Ichikawa, Hiroshi Onishi, Masanori Matsuda, Tetsuya Wakayama, Nobuyuki Enomoto, Utaroh Motosugi, Tatsuya Shimizu, Naoki Oishi |
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Rok vydání: | 2018 |
Předmět: |
Gadolinium DTPA
Male Pathology medicine.medical_specialty Gadoxetic acid Carcinoma Hepatocellular Contrast Media 030218 nuclear medicine & medical imaging 03 medical and health sciences Hepatic Artery 0302 clinical medicine Text mining Image Processing Computer-Assisted medicine Humans Radiology Nuclear Medicine and imaging Aged Retrospective Studies Aged 80 and over Ring (mathematics) business.industry Liver Neoplasms Reproducibility of Results General Medicine Middle Aged Image Enhancement medicine.disease Magnetic Resonance Imaging digestive system diseases 030220 oncology & carcinogenesis Hepatocellular carcinoma Female business Nuclear medicine Differential (mathematics) medicine.drug Arterial phase |
Zdroj: | Investigative Radiology. 53:191-199 |
ISSN: | 1536-0210 0020-9996 |
Popis: | The aim of this study was to evaluate the efficacy of multiphasic hepatic arterial phase (HAP) imaging using DISCO (differential subsampling with Cartesian ordering) in increasing the confidence of diagnosis of hepatocellular carcinoma (HCC).This retrospective study was approved by the institutional review board, and the requirement for informed patient consent was waived. Consecutive patients (from 2 study periods) with malignant liver nodules were examined by gadoxetic acid-enhanced magnetic resonance imaging using either multiphasic (6 phases; n = 135) or single (n = 230) HAP imaging, which revealed 519 liver nodules other than benign ones (HCC, 497; cholangiocarcinoma, 11; metastases, 10; and malignant lymphoma, 1). All nodules were scored in accordance with the Liver Imaging Reporting and Data System (LI-RADS v2014), with or without consideration of ring-like enhancement in multiphasic HAP images as a major feature.In the multiphasic HAP group, 178 of 191 HCCs were scored as LR-3 to LR-5 (3 [1.69%], 85 [47.8%], and 90 [50.6%], respectively). Upon considering ring-like enhancement in multiphasic HAP images as a major feature, 5 more HCCs were scored as LR-5 (95 [53.4%]), which was a significantly more confident diagnosis than that with single HAP images (295 of 306 HCCs scored as LR-3 to LR-5: 13 [4.41%], 147 [49.8%], and 135 [45.8%], respectively; P = 0.0296). There was no significant difference in false-positive or false-negative diagnoses between the multiphasic and single HAP groups (P = 0.8400 and 0.1043, respectively).Multiphasic HAP imaging can improve the confidence of diagnosis of HCCs in gadoxetic acid-enhanced magnetic resonance imaging. |
Databáze: | OpenAIRE |
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