The effect of hyaluronidase on ultrasound-measured dispersal of local anaesthetic following sub-Tenon injection
| Autor: | S Ahmed, H. McLure, I G Simmons, S Goel, M Khandwala |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
medicine.medical_specialty
Lidocaine Eye Movements medicine.drug_class Hyaluronoglucosaminidase Cataract Extraction Eye law.invention Injections Randomized controlled trial Double-Blind Method Hyaluronidase law medicine Humans Prospective Studies Anesthetics Local Prospective cohort study Aged Ultrasonography Local anaesthetic business.industry Local anesthetic Ultrasound Surgery Ophthalmology Exact test Anesthesia business medicine.drug Anesthesia Local |
| Zdroj: | Eye (London, England). 22(8) |
| ISSN: | 0950-222X |
| Popis: | To determine by B-scan ultrasonography if the addition of hyaluronidase affects the dispersal of anaesthetic fluid after sub-Tenon's injection. Single-centre prospective randomised double-blind study. We performed a trial in 19 patients who were randomised to receive 5 ml of lidocaine 2% alone, or with hyaluronidase 15 IU/ml. A pre-anaesthetic B-scan ultrasound was performed followed by a standard infero-nasal sub-Tenon's injection. Further B-scan ultrasound studies were performed at 1, 3, and 5 min recording depth of local anaesthetic fluid. Data was analysed with Fisher's exact test and Student's t-test where appropriate. Results were considered significant when P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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