Sensitization to benzyl salicylate and other allergens in patients with frontal fibrosing alopecia
| Autor: | Jaime Martínez‐Mariscal, Consuelo Sánchez-Herreros, María A Pastor-Nieto, Aránzazu Vergara-Sánchez, Esther De Eusebio-Murillo, María E. Gatica-Ortega |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Photopatch test Population Dermatology Scarring alopecia Cosmetics 030207 dermatology & venereal diseases 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Immunology and Allergy Medicine Humans 030212 general & internal medicine education Allergic contact dermatitis Sensitization Aged Retrospective Studies Benzyl salicylate Aged 80 and over education.field_of_study business.industry Dermatitis Photoallergic Frontal fibrosing alopecia Pruritus Patch test Alopecia Allergens Middle Aged medicine.disease Salicylates medicine.anatomical_structure chemistry Spain Dermatitis Allergic Contact Odorants Quality of Life Female business Sunscreening Agents |
| Zdroj: | Contact dermatitisREFERENCES. 84(6) |
| ISSN: | 1600-0536 |
| Popis: | Introduction Contact sensitization is frequent among frontal fibrosing alopecia (FFA) patients (52-76%). Objective To evaluate the frequency of sensitization/photosensitization among an FFA population. Material and methods A population of FFA patients were patch tested (GEIDAC baseline; cosmetic and fragrance series), and photopatch tested (sunscreens series). Results 36 patients (mean age: 64.6 years old; 35/36: women) were studied. History of dermatitis was recorded in 69.4% (frequently involving the face). Overall, 80.5% patients showed positive patch test reactions. The most frequently positive allergens were nickel sulphate (25%); benzyl salicylate (22%); gallates (16.6%); propolis (16.6%); and limonene hydroperoxides (13.8%). Benzyl salicylate was likely relevant to the dermatitis (labelled on personal care products and most patients reporting clinical improvement with allergen avoidance). Patch tests with sunscreens showed positive reactions to 11 materials (5 patients). Photopatch tests were positive in one case. Discussion We speculate a possible relationship between sensitization to benzyl salicylate and FFA. Hypothetically, the most likely explanation is that sensitization to benzyl salicylate involving FFA patients is a consequence of increased exposure to it. It is unclear whether allergenic avoidance may impact the prognosis of alopecia. However, it seems to significantly improve the patients' quality of life by lessening dermatitis and pruritus. This article is protected by copyright. All rights reserved. |
| Databáze: | OpenAIRE |
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