The comparison of dual phase Tc-99m MIBI and tc-99m MDP scintimammography in the evaluation of breast masses: preliminary report
| Autor: | Sabri Dundar, Nuri Arslan, Emel Öztürk, Hikmet Bayhan, Seyfettin Ilgan, Mesut Pekcan, Turgut Tufan, Yavuz Narin |
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| Rok vydání: | 2000 |
| Předmět: |
Adult
Technetium Tc 99m Sestamibi medicine.medical_specialty Tc-99m MIBI Breast Neoplasms Technetium Tc 99m Medronate Sensitivity and Specificity Isotopes of technetium Breast cancer Preliminary report Predictive Value of Tests Technetium-99 Medicine Humans Radiology Nuclear Medicine and imaging Breast Prospective cohort study Radionuclide Imaging Aged Aged 80 and over Scintimammography business.industry Reproducibility of Results General Medicine Middle Aged medicine.disease Lymphatic Metastasis Tc 99m mdp Female Radiology Lymph Nodes Radiopharmaceuticals business Nuclear medicine Mammography |
| Zdroj: | Annals of nuclear medicine. 14(1) |
| ISSN: | 0914-7187 |
| Popis: | The aim of this prospective study was to determine the diagnostic value of Tc-99m MDP scintimammography (SMG) for the detection of breast cancer in patients with breast masses and to compare the results with Tc-99m MIBI scintimammography. Twenty patients, categorized as suspicious, positive or benign for breast cancer according to the mammographic findings were included in the study. Dual phase Tc-99m MIBI and Tc-99m MDP SMG were performed in the prone lateral position within 5 days of each other. Although early and late Tc-99m MIBI SMG showed equal (90.4%) sensitivity, the specificity of late Tc-99m MIBI (87.5%) was found superior to early (62.5%) imaging. The overall sensitivity and specificity of early Tc-99m MDP SMG were 71.4% and 62.5%, respectively. Although late Tc-99m MDP imaging showed 100% specificity, its sensitivity was only 23.8%. In the patients with palpable masses, both early Tc-99m MDP and Tc-99m MIBI showed equal sensitivity (100%), but the sensitivity of early Tc-99m MIBI (37.5%) was found slightly higher than Tc-99m MDP (25.0%) for nonpalpable breast lesions. The sensitivity of Tc-99m MIBI and Tc-99m MDP SMG in detecting metastatic axillary involvement was 66.6% and 50%, respectively. High sensitivity and specificity together with its low cost, easy availability and the possibility of detecting bone metastases seems to make Tc-99m MDP a contributive agent in the evaluation of breast lesions as an alternative to Tc-99m MIBI. |
| Databáze: | OpenAIRE |
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