Antimicrobial-Resistant Pathogens Associated With Healthcare-Associated Infections: Summary of Data Reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2011–2014
| Autor: | Lindsey M. Weiner, Amy K. Webb, Brandi Limbago, Margaret A. Dudeck, Jean Patel, Alexander J. Kallen, Jonathan R. Edwards, Dawn M. Sievert |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Cross Infection Gram-Negative Facultatively Anaerobic Rods Epidemiology 030106 microbiology Pneumonia Ventilator-Associated Gram-Positive Bacteria Article Hospitals United States Anti-Bacterial Agents 03 medical and health sciences 0302 clinical medicine Infectious Diseases Gram-Negative Aerobic Rods and Cocci Catheter-Related Infections Drug Resistance Multiple Bacterial Urinary Tract Infections Central Venous Catheters Humans Surgical Wound Infection 030212 general & internal medicine Centers for Disease Control and Prevention U.S |
| ISSN: | 0899-823X |
| Popis: | OBJECTIVETo describe antimicrobial resistance patterns for healthcare-associated infections (HAIs) that occurred in 2011–2014 and were reported to the Centers for Disease Control and Prevention’s National Healthcare Safety Network.METHODSData from central line–associated bloodstream infections, catheter-associated urinary tract infections, ventilator-associated pneumonias, and surgical site infections were analyzed. These HAIs were reported from acute care hospitals, long-term acute care hospitals, and inpatient rehabilitation facilities. Pooled mean proportions of pathogens that tested resistant (or nonsusceptible) to selected antimicrobials were calculated by year and HAI type.RESULTSOverall, 4,515 hospitals reported that at least 1 HAI occurred in 2011–2014. There were 408,151 pathogens from 365,490 HAIs reported to the National Healthcare Safety Network, most of which were reported from acute care hospitals with greater than 200 beds. Fifteen pathogen groups accounted for 87% of reported pathogens; the most common included Escherichia coli (15%), Staphylococcus aureus (12%), Klebsiella species (8%), and coagulase-negative staphylococci (8%). In general, the proportion of isolates with common resistance phenotypes was higher among device-associated HAIs compared with surgical site infections. Although the percent resistance for most phenotypes was similar to earlier reports, an increase in the magnitude of the resistance percentages among E. coli pathogens was noted, especially related to fluoroquinolone resistance.CONCLUSIONThis report represents a national summary of antimicrobial resistance among select HAIs and phenotypes. The distribution of frequent pathogens and some resistance patterns appear to have changed from 2009–2010, highlighting the need for continual, careful monitoring of these data across the spectrum of HAI types.Infect Control Hosp Epidemiol 2016;1–14 |
| Databáze: | OpenAIRE |
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