The impact of insecticide-treated school uniforms on dengue infections in school-aged children: study protocol for a randomised controlled trial in Thailand
| Autor: | Yesim Tozan, Annelies Wilder-Smith, Phanthip Olanratmanee, Pongsri Maskhao, Peter Byass, Pattamaporn Kittayapong, Valérie R. Louis, James G. Logan, Luechai Sringernyuang, Duane J. Gubler, Sarah J. Banks, Steve W. Lindsay |
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| Jazyk: | angličtina |
| Předmět: |
Research design
Insecticides Veterinary medicine Time Factors Cost effectiveness Cost-Benefit Analysis Medicine (miscellaneous) Disease Vectors law.invention Dengue fever Dengue Insecticide-treated clothes Study Protocol 610 Medical sciences Medicine 0302 clinical medicine Protective Clothing Randomized controlled trial law School children Pharmacology (medical) 030212 general & internal medicine Child lcsh:R5-920 Cross-Over Studies Schools Randomised control trial Cost–benefit analysis Incidence Incidence (epidemiology) Public Health Global Health Social Medicine and Epidemiology Health Care Costs Thailand 3. Good health Research Design Seasons 370 Education lcsh:Medicine (General) School uniforms Adolescent 030231 tropical medicine education Developing country Insect Control Vulnerable Populations 03 medical and health sciences Double-Blind Method Environmental health medicine Animals Humans Developing Countries Permethrin business.industry medicine.disease Crossover study Folkhälsovetenskap global hälsa socialmedicin och epidemiologi business |
| Zdroj: | Trials, Vol 13, Iss 1, p 212 (2012) Trials, 2012, Vol.13(11), pp.212 [Peer Reviewed Journal] Trials; Vol 13 Trials |
| ISSN: | 1745-6215 |
| DOI: | 10.1186/1745-6215-13-212 |
| Popis: | Background There is an urgent need to protect children against dengue since this age group is particularly sensitive to the disease. Since dengue vectors are active mainly during the day, a potential target for control should be schools where children spend a considerable amount of their day. School uniforms are the cultural norm in most developing countries, worn throughout the day. We hypothesise that insecticide-treated school uniforms will reduce the incidence of dengue infection in school-aged children. Our objective is to determine the impact of impregnated school uniforms on dengue incidence. Methods A randomised controlled trial will be conducted in eastern Thailand in a group of schools with approximately 2,000 students aged 7–18 years. Pre-fabricated school uniforms will be commercially treated to ensure consistent, high-quality insecticide impregnation with permethrin. A double-blind, randomised, crossover trial at the school level will cover two dengue transmission seasons. Discussion Practical issues and plans concerning intervention implementation, evaluation, analysing and interpreting the data, and possible policy implications arising from the trial are discussed. Trial registration clinicaltrial.gov. Registration number: NCT01563640 |
| Databáze: | OpenAIRE |
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