Synthesis of chondroitin sulfate by the human cervix during the menstrual cycle
| Autor: | Nichols Vorys, Richard P. Dickey, Vernon C. Stevens, John C. Ullery, Charles W. Denko |
|---|---|
| Rok vydání: | 1966 |
| Předmět: |
medicine.medical_specialty
media_common.quotation_subject Cervix Uteri chemistry.chemical_compound Internal medicine Sulfur Isotopes Follicular phase medicine Humans Chondroitin sulfate Radiometry Cervix Menstrual cycle media_common Sulfates business.industry Estrogen secretion Ground substance Obstetrics and Gynecology Estrogens In vitro Menstruation Uterine Cervicitis Endocrinology medicine.anatomical_structure chemistry Endometrial Hyperplasia Uterine Neoplasms Female business Chondroitin Corpus luteum |
| Zdroj: | American Journal of Obstetrics and Gynecology. 95:959-962 |
| ISSN: | 0002-9378 |
| Popis: | 1.1. The rate of S 35 uptake by the human cervix in vitro was measured as an indication of the chondroitin sulfate synthesis in the ground substance of this tissue. 2.2. Rates of S 35 uptake were high in specimens removed during the proliferative phase of the normal menstrual cycle. 3.3. Rates of S 35 uptake were low during the secretory phase of the cycle in an inverse relationship to presumed progesterone production by the corpus luteum. 4.4. Some estrogen secretion was necessary for elevated S 35 uptake. Low uptake rates were observed in specimens from patients with atrophic endometria. 5.5. Similarities between these findings and studies by others on cervical dilatation and effacement during the normal menstrual cycle are discussed. |
| Databáze: | OpenAIRE |
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