Vitamin D deficiency in patients with osteoarthritis undergoing total hip replacement

Autor: Richard Keen, Danyal H. Nawabi, Fares S. Haddad, K. F. Chin
Rok vydání: 2010
Předmět:
Zdroj: The Journal of Bone and Joint Surgery. British volume. :496-499
ISSN: 2044-5377
0301-620X
DOI: 10.1302/0301-620x.92b3.23535
Popis: We measured the plasma 25-hydroxyvitamin D3 (25(OH)D3) levels in 62 consecutive Caucasian patients undergoing total hip replacement for osteoarthritis. The patients were divided into two groups based on whether they were vitamin D sufficient or deficient. The groups were matched for age, gender and the American Society of Anaesthesiologists (ASA) grade. The prevalence of vitamin D deficiency in our patients was comparable with recent population-based studies performed in the United Kingdom. Patients with vitamin D deficiency had lower pre-operative Harris hip scores (Mann-Whitney test, p = 0.018) and were significantly less likely to attain an excellent outcome from total hip replacement (chi-squared test, p = 0.038). Vitamin D levels were found to positively correlate with both pre- and post-operative Harris hip scores. These results warrant further study of vitamin D deficiency in patients undergoing joint replacement as it is a risk factor for a suboptimal outcome which is relatively simple and cheap to correct.
Databáze: OpenAIRE