Effect of zinc on cadmium influx and toxicity in cultured CHO cells

Autor:	P. C. Huang, Alice J. Corrigan, Patricia Bohdan, Betty Smith
Rok vydání:	1980
Předmět:	inorganic chemicals Cadmium Chemistry Endocrinology Diabetes and Metabolism Chinese hamster ovary cell Biochemistry (medical) Clinical Biochemistry Inorganic chemistry chemistry.chemical_element General Medicine Zinc Biochemistry Inorganic Chemistry Transition metal Toxicity Protein biosynthesis Antagonism Cell survival
Zdroj:	Biological trace element research. 2(3)
ISSN:	0163-4984
Popis:	Addition of zinc lowers the toxicity level of cadmium in cultured CHO cells. Cell survival and protein synthesis were used to measure the cellular toxicity of cadmium.(109)Cd was used to measure cadmium uptake by the cells. The results suggest that these class IIB transition metals, zinc and cadmium, share a common transport mechanism. Thus, the antagonism appears to involve a reduction in the influx of cadmium due to the presence of zinc.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7de0819c0c92524d72d253e397f17142 https://pubmed.ncbi.nlm.nih.gov/24271270 Zobrazit plný text záznamu Full text from SpringerLink