The involvement of left inferior frontal and middle temporal cortices in word production unveiled by greater facilitation effects following brain damage

Autor: Grégoire Python, Bertrand Glize, Marina Laganaro
Rok vydání: 2018
Předmět:
Adult
Male
Vocabulary
Cognitive Neuroscience
media_common.quotation_subject
Repetition priming
Experimental and Cognitive Psychology
Brain damage
Semantics
050105 experimental psychology
Young Adult
03 medical and health sciences
Behavioral Neuroscience
0302 clinical medicine
Aphasia
Repetition Priming
medicine
Humans
Speech
0501 psychology and cognitive sciences
Aged
Aphasia/diagnostic imaging
Aphasia/etiology
Aphasia/physiopathology
Female
Frontal Lobe/diagnostic imaging
Frontal Lobe/physiopathology
Magnetic Resonance Imaging
Middle Aged
Pattern Recognition
Visual/physiology
Repetition Priming/physiology
Speech/physiology
Stroke/complications
Stroke/diagnostic imaging
Stroke/physiopathology
Temporal Lobe/diagnostic imaging
Temporal Lobe/physiopathology
Language production
Left inferior frontal cortex
Left middle temporal cortex
Semantic priming
Word production
media_common
05 social sciences
Temporal Lobe
Frontal Lobe
Stroke
Pattern Recognition
Visual
Facilitation
medicine.symptom
Psychology
030217 neurology & neurosurgery
Cognitive psychology
Zdroj: Neuropsychologia, vol. 121, pp. 122-134
ISSN: 0028-3932
DOI: 10.1016/j.neuropsychologia.2018.10.026
Popis: In stroke-induced aphasia, left hemispheric lesions generally disturb the word production network. The left inferior frontal gyrus (LIFG) and the left middle temporal gyrus (LMTG) are involved in word production, but their respective contribution remains ambiguous. Previous investigations have largely focused on semantic interference to gather information about word production. Here we assessed the sensitivity of twenty-five aphasic speakers with either LIFG or LMTG lesions and matched controls to both semantic facilitation and interference in word production using the picture-word (PWP) and the blocked-cyclic naming (BCNP) paradigms. In the PWP (Exp. 1), semantic facilitation was exaggerated in participants with LIFG damage as compared to age-matched controls. In the BCNP (Exp. 2), repetition priming on production speed was larger in participants with LMTG damage than in controls, without any decrease of semantic errors. In the light of the results in the PWP, the LIFG appears to be a necessary structure to shape semantic facilitation. It might play an important role in properly adjusting the lexical selection threshold within the word production network. The results in the BCNP suggest that the LMTG conveys semantic-to-lexical connections likely involved in repetition priming and in mapping concepts to their correct lexical label. As consequences, participants with LIFG lesions possibly rely more on strategic vs automatic processes to efficiently select lexical entries in semantically competitive contexts, whereas participants with LMTG might exploit residual semantic-to-lexical activation.
Databáze: OpenAIRE
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