Pectoral Fascia Preservation in Oncological Mastectomy to Reduce Complications and Improve Reconstructions
| Autor: | N.M.A. Krekel, Jaco Suijker, Ralph de Vries, Monique P van den Tol, Yara L. Blok |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Reconstructive surgery business.industry medicine.medical_treatment Postoperative complication Original Articles 030230 surgery medicine.disease Prosthesis Surgery law.invention 03 medical and health sciences 0302 clinical medicine Systematic review medicine.anatomical_structure Randomized controlled trial law 030220 oncology & carcinogenesis Seroma medicine business Pectoral fascia Mastectomy |
| Zdroj: | Plastic and Reconstructive Surgery Global Open |
| ISSN: | 2169-7574 |
| Popis: | Background: Excision of the pectoral fascia (PF) is routinely performed in oncological mastectomies. Preservation of the PF may, however, decrease postoperative complication rates for bleeding, infections, and seroma. It may also improve reconstructive outcomes by better prosthesis coverage, thereby reducing implant extrusion rates and improving cosmetic outcomes. Methods: A systematic review according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis principles was performed. Studies describing PF preservation were searched in 3 databases. All studies including more than 10 patients were included. The main outcomes were oncological safety (local recurrence, regional and distant metastases, and mortality rates), complication rates (bleeding, infections, seroma), loss of the prosthesis after reconstructive surgery, and cosmetic outcomes following reconstruction. Results: Five studies were included. Three reported on 2 different randomized controlled trials (n = 73, and n = 244), and 2 studies were retrospective case series (n = 203 and n = 256). PF preservation did not affect oncological outcomes in terms of local recurrences, regional and distant metastases, or mortality rates. One study described a significantly lower incidence of seroma in the PF preservation group. No differences were found for bleeding complications and infections. No objective data were provided for reconstructive complications or cosmetic outcomes. Conclusions: The literature on PF preservation is scarce. Based on the current evidence, PF preservation seems oncologically safe while potentially reducing postoperative complication rates. It is expected that reconstructive outcomes will benefit from PF preservation, but these studies lack evidence on this topic. Future studies should provide insight into all aspects of PF preservation. |
| Databáze: | OpenAIRE |
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