Activating effect of Tanacetum vulgare L. pectin polysaccharide on ionic channels of neuronal membrane
Autor: | A. Ya. Polle, V. I. Prosheva, A. I. Vislobokov |
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Rok vydání: | 2004 |
Předmět: |
food.ingredient
Pectin Tanacetum vulgare L Sodium Potassium Ionic bonding chemistry.chemical_element Lymnaea stagnalis In Vitro Techniques Calcium Polysaccharide Ion Channels General Biochemistry Genetics and Molecular Biology Tanacetum food Animals Lymnaea Neurons chemistry.chemical_classification Chromatography biology Chemistry Cell Membrane General Medicine biology.organism_classification Kinetics Pectins |
Zdroj: | Bulletin of Experimental Biology and Medicine. 138:390-392 |
ISSN: | 1573-8221 0007-4888 |
Popis: | The membranotropic effects of TVF tanacetan pectin polysaccharide derived from Tanacetum vulgare L. was studied by the voltage-clamp method on isolated neurons of Lymnaea stagnalis mollusk. TVF in concentrations of 0.1-10.0 microg/ml nonselectively activated the outward potassium and total inward (sodium and calcium) ionic currents (slightly dose-dependently and reversibly increased their amplitude by 5-10%) and decreased nonspecific leakage current. |
Databáze: | OpenAIRE |
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