Activating effect of Tanacetum vulgare L. pectin polysaccharide on ionic channels of neuronal membrane

Autor: A. Ya. Polle, V. I. Prosheva, A. I. Vislobokov
Rok vydání: 2004
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 138:390-392
ISSN: 1573-8221
0007-4888
Popis: The membranotropic effects of TVF tanacetan pectin polysaccharide derived from Tanacetum vulgare L. was studied by the voltage-clamp method on isolated neurons of Lymnaea stagnalis mollusk. TVF in concentrations of 0.1-10.0 microg/ml nonselectively activated the outward potassium and total inward (sodium and calcium) ionic currents (slightly dose-dependently and reversibly increased their amplitude by 5-10%) and decreased nonspecific leakage current.
Databáze: OpenAIRE