The outcomes of children with pediatric acute respiratory distress syndrome: proceedings from the Pediatric Acute Lung Injury Consensus Conference
| Autor: | Michael W, Quasney, Yolanda M, López-Fernández, Miriam, Santschi, R Scott, Watson, Melania, Bembea |
|---|---|
| Přispěvatelé: | Critical care, Anesthesiology, Peri-operative and Emergency medicine (CAPE), Rimensberger, Peter |
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Treatment outcome MEDLINE Acute respiratory distress Comorbidity Lung injury Critical Care and Intensive Care Medicine Intensive Care Units Pediatric Cognition Respiratory Distress Syndrome Newborn/complications Newborn/complications medicine Humans Family Intensive care medicine Pediatric Respiratory Distress Syndrome Newborn Respiratory Distress Syndrome Behavior ddc:618 business.industry Consensus conference Length of Stay medicine.disease Prognosis Respiratory Function Tests Intensive Care Units Mental Health Treatment Outcome Pediatrics Perinatology and Child Health Acute Disease Nervous System Diseases/etiology Nervous System Diseases business Biomarkers |
| Zdroj: | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 16(5 Suppl 1), S118-S131. LIPPINCOTT WILLIAMS & WILKINS Pediatric Critical Care Medicine, Vol. 16, No 5 Suppl 1 (2015) pp. S118-131 |
| ISSN: | 1529-7535 |
| Popis: | OBJECTIVE: To provide additional details and evidence behind the recommendations for outcomes assessment of patients with pediatric acute respiratory distress syndrome from the Pediatric Acute Lung Injury Consensus Conference.DESIGN: Consensus conference of experts in pediatric acute lung injury.METHODS: A panel of 27 experts met over the course of 2 years to develop a taxonomy to define pediatric acute respiratory distress syndrome and to make recommendations regarding treatment and research priorities. The outcomes subgroup comprised four experts. When published data were lacking, a modified Delphi approach emphasizing strong professional agreement was used.RESULTS: The Pediatric Acute Lung Injury Consensus Conference experts developed and voted on a total of 151 recommendations addressing the topics related to pediatric acute respiratory distress syndrome, seven of which related to outcomes after pediatric acute respiratory distress syndrome. All seven recommendations had strong agreement. Children with acute respiratory distress syndrome continue to have a high mortality, specifically, in relation to certain comorbidities and etiologies related to pediatric acute respiratory distress syndrome. Comorbid conditions, such as an immunocompromised state, increase the risk of mortality even further. Likewise, certain etiologies, such as non-pulmonary sepsis, also place children at a higher risk of mortality. Significant long-term effects were reported in adult survivors of acute respiratory distress syndrome: diminished lung function and exercise tolerance, reduced quality of life, and diminished neurocognitive function. Little knowledge of long-term outcomes exists in children who survive pediatric acute respiratory distress syndrome. Characterization of the longer term consequences of pediatric acute respiratory distress syndrome in children is vital to help identify opportunities for improved therapeutic and rehabilitative strategies that will lessen the long-term burden of pediatric acute respiratory distress syndrome and improve the quality of life in children.CONCLUSIONS: The Consensus Conference developed pediatric-specific recommendations for pediatric acute respiratory distress syndrome regarding outcome measures and future research priorities. These recommendations are intended to promote optimization and consistency of care for children with pediatric acute respiratory distress syndrome and identify areas of uncertainty requiring further investigation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|