Genetic differences in temperament determine whether lavender oil alleviates or exacerbates anxiety in sheep

Autor: C. Fiol, Dominique Blache, P.A.R. Hawken
Rok vydání: 2012
Předmět:
Zdroj: Physiology & Behavior. 105:1117-1123
ISSN: 0031-9384
DOI: 10.1016/j.physbeh.2011.12.005
Popis: Growing concerns about the risk of addiction to benzodiazepines have led to increasing interest in alternative therapies to treat anxiety and depression. Lavender oil (Lavendula augustifolia) is reportedly anxiolytic in a number of species but little is known about how it affects individuals that are more or less anxious when faced with a stressor. In this study, we used changes in locomotor activity and the plasma concentrations of cortisol to test whether lavender oil would reduce behavioral and endocrine correlates of anxiety in calm and nervous sheep exposed to an isolation stressor. During the non-breeding season, 'calm' or 'nervous' female sheep from the UWA temperament flock were exposed to a mask containing either 1 mL of 10% lavender oil (calm: n=8; nervous: n=8) or peanut oil (calm: n=8; nervous: n=8). After 30 min, each sheep was isolated for 5 min and then returned to the group. Blood was sampled prior to the mask, prior to isolation, 1 min and 30 min after isolation to profile changes in the plasma concentrations of cortisol. Agitation score, locomotor activity and vocalizations were recorded as correlates of anxiety associated with the isolation stressor. Irrespective of whether they were exposed to lavender oil, calm sheep had a lower agitation score (P
Databáze: OpenAIRE