Underestimation of cancer in case of diagnosis of atypical ductal hyperplasia (ADH) by vacuum assisted core needle biopsy
| Autor: | Michał Michalak, Paweł Kurzawa, Dawid Murawa, Paweł Murawa, Karol Polom |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Core needle
Cancer Research Pathology medicine.medical_specialty medicine.diagnostic_test business.industry Vacuum assisted Cancer Atypical ductal hyperplasia medicine.disease Core biopsy Breast cancer Oncology Radiology Nuclear Medicine and imaging Biopsy medicine Mammography Radiology Nuclear Medicine and imaging Ductal Hyperplasia Original Research Article sense organs skin and connective tissue diseases business |
| Zdroj: | Reports of Practical Oncology & Radiotherapy. 17:129-133 |
| ISSN: | 1507-1367 |
| DOI: | 10.1016/j.rpor.2012.03.008 |
| Popis: | BackgroundWith the introduction of mammography screening, we are more often dealing with the diagnosis of precancerous and preinvasive breast lesions. An increasing number of patients are observed to show a premalignant change of ADH (atypical ductal hyperplasia). It also involves a wider use of the vacuum assisted core biopsy as a tool for verifying nonpalpable changes identified by mammography.AimThis paper describes our experience of 134 cases of ADH diagnosed at Mammotome® vacuum core needle biopsy.Material and methodsOf 4326 mammotomic biopsies performed at our institution in 2000–2006, ADH was diagnosed in 134 patients (3.1%). Patients underwent surgery to remove the suspected lesion. All histopathological blocks were again reviewed by one pathologist. Clinical, radiological and pathological data were collected for statistical evaluation.ResultsUnderestimation of invasive changes occurred in 12 patients (9%). The only clinicopathologic feature of statistical significance radiologically and pathologically was the presence of radial scar in the mammography.ConclusionsMore frequent diagnosis of precancerous changes in the mammotomic breast biopsy forces us to establish a clear clinical practice. The problem is the underestimation of invasive changes. The occurrence of radial scar on mammography for diagnosis of the presence of ADH increases the risk of invasive changes. |
| Databáze: | OpenAIRE |
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