Antiallergic dimeric prenylbenzoquinones from Ehretia microphylla
| Autor: | Hideaki Otsuka, William G. Padolina, Satoshi Yamamura, Lourdes R. Simpol, Koichiro Ozawa, Kazuo Yamasaki, Ryoji Kasai, Kazuhiro Ohtani |
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| Rok vydání: | 1995 |
| Předmět: |
Magnetic Resonance Spectroscopy
Stereochemistry Philippines Chemical structure Histamine Antagonists Plant Science Spectrometry Mass Fast Atom Bombardment Horticulture Pharmacognosy Biochemistry Exocytosis Ehretia microphylla Benzoquinones Animals Organic chemistry Molecular Biology Plants Medicinal biology Chemistry Biological activity General Medicine Boraginaceae Nuclear magnetic resonance spectroscopy Allergens Fast atom bombardment biology.organism_classification Rats |
| Zdroj: | Phytochemistry. 39:105-110 |
| ISSN: | 0031-9422 |
| DOI: | 10.1016/0031-9422(94)00845-k |
| Popis: | The ethyl acetate-soluble portion of the MeOH extract of Ehretia microphylla showed inhibitory activity on exocytosis in antigen-stimulated rat basophils. The bioassay-guided separation of this fraction afforded five biologically active compounds. By means of chemical and spectroscopic methods, the structures of these compounds, which include microphyllone, a unique dimeric prenylbenzoquinone, and its congeners, were elucidated. |
| Databáze: | OpenAIRE |
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