Adaptation of the Cutaneous Microcirculation in Preterm Neonates
| Autor: | Hugo A. van Elteren, Irwin K M Reiss, Joost van Rosmalen, Rogier C. J. de Jonge, Can Ince |
|---|---|
| Přispěvatelé: | Other departments, Amsterdam Cardiovascular Sciences, Translational Physiology, Pediatric surgery, Pediatrics, Epidemiology, Intensive Care |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty Physiology Hemodynamics Cutaneous microcirculation Gestational Age 030204 cardiovascular system & hematology Microcirculation 03 medical and health sciences 0302 clinical medicine Peripheral perfusion 030225 pediatrics Physiology (medical) Internal medicine Medicine Humans OXYGEN EXPOSURE Molecular Biology Skin Fetus business.industry Infant Newborn Gestational age Adaptation Physiological Oxygen Postnatal age Cardiology Blood Vessels Female Cardiology and Cardiovascular Medicine business Infant Premature |
| Zdroj: | Microcirculation (New York, N.Y., 23(6), 468-474. Wiley-Blackwell Microcirculation, 23(6), 468-474. Wiley-Blackwell van Elteren, H A, de Jonge, R C J, van Rosmalen, J, Ince, C & Reiss, I K M 2016, ' Adaptation of the Cutaneous Microcirculation in Preterm Neonates ', Microcirculation, vol. 23, no. 6, pp. 468-474 . https://doi.org/10.1111/micc.12295 |
| ISSN: | 1073-9688 |
| DOI: | 10.1111/micc.12295 |
| Popis: | OBJECTIVE Transition from fetal to neonatal circulation is characterized by multiple hemodynamic changes. The role of the microcirculation in this process is underexposed. Visualizing the cutaneous microcirculation can help us understand peripheral perfusion in a noninvasive manner. METHODS Cutaneous microcirculation of term and preterm infants born below 32 weeks of GA was measured in the first month of life using IDF imaging. Linear mixed modeling was used to identify clinical variables which influence the cutaneous microcirculation. RESULTS Sixty preterm and 33 term infants were included. TVD of preterm infants significantly decreased in the first month of life (31.7 mm/mm(2) day 1 vs 27.9 mm/mm(2) day 28), but remained significantly higher compared to TVD of term infants on day 1 (25.8 mm/mm(2) ). Besides postnatal age, no clinical variables were associated with TVD. Infants born SGA had significantly higher TVD values directly after birth than those born appropriate for GA (35.4 mm/mm(2) vs 31.6 mm/mm(2) ; p = 0.015). CONCLUSIONS TVD decreases in the first month after birth and is higher in preterm infants compared to those born term. Differences in antenatal oxygen exposure might explain the adaptation of the microcirculation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text