Predictive utility of postoperative serum myoglobin in acute kidney injury after liver transplantation
| Autor: | Qi Ding, Song Zhao, Jin Zhang, Kai Yu, Yue Zheng, Xin Xin, Rong-Yue Gao, Lifeng Huang, Wen-Xiong Li, Yu-Zhen Han |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
medicine.medical_specialty medicine.medical_treatment Liver transplantation urologic and male genital diseases Gastroenterology law.invention Postoperative Complications law Risk Factors Internal medicine medicine Humans Risk factor Retrospective Studies Advanced and Specialized Nursing biology business.industry Myoglobin Incidence (epidemiology) Acute kidney injury Acute Kidney Injury Length of Stay medicine.disease Intensive care unit female genital diseases and pregnancy complications Confidence interval Liver Transplantation Anesthesiology and Pain Medicine Alanine transaminase biology.protein Complication business |
| Zdroj: | Annals of palliative medicine. 10(11) |
| ISSN: | 2224-5839 |
| Popis: | BACKGROUND Acute kidney injury (AKI) is a common and multifactorial complication after liver transplantation (LT). Myoglobin (Mb) which can be served as O2 storage and delivery depot is present in muscles and cardiac myocytes. Previous studies had shown the close relationship between Mb and AKI. But there is a lack of clinical studies for Mb with the risk of AKI due to LT. This study was performed to determine the association between the serum level of Mb and incidence of AKI in patients underwent LT. METHODS The clinical data of 140 consecutive adult patients who underwent LT at our center from June 2018 to August 2020 were analyzed in this study. One hundred and fifteen patients met the inclusion criteria. The performances of postoperative laboratory variables (including serum Mb) were evaluated. The outcomes after LT, including the duration of intensive care unit (ICU) stay, hospital stay and 28-day mortality, were also measured. RESULTS We divided 115 patients into AKI group (n=44) and non-AKI group (n=71). Serum Mb on postoperative day 0 (POD0) was significantly higher in AKI group than those in non-AKI group (P |
| Databáze: | OpenAIRE |
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