A sublethal dose of the neonicotinoid insecticide acetamiprid reduces sperm density in a songbird
| Autor: | J. Sire, Fabrice Helfenstein, Ophélie Gning, Gaétan Glauser, Ségolène Humann-Guilleminot, S. Grünig, C. Tassin de Montaigu, Armelle Vallat |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Insecticides 010501 environmental sciences Biology 01 natural sciences Biochemistry Acetamiprid Songbirds 03 medical and health sciences chemistry.chemical_compound Neonicotinoids 0302 clinical medicine Animal science Ingestion Animals Humans 030212 general & internal medicine Zebra finch 0105 earth and related environmental sciences General Environmental Science Dose-Response Relationship Drug Sperm Count Neonicotinoid Pesticide biology.organism_classification Sperm Spermatozoa Songbird chemistry Toxicity |
| Zdroj: | Environmental research. 177 |
| ISSN: | 1096-0953 |
| Popis: | Farmland bird species are particularly exposed to pesticides through various pathways. Among pesticides, neonicotinoids insecticides are commonly used in agriculture, but their influence on bird reproductive capacities is poorly understood. In this study, we experimentally tested the effects of the neonicotinoid acetamiprid on House sparrows' sperm quality and oxidative status following ingestion of a low and field-realistic dose of the compound. To do so, 56 males were captured, held and orally dosed seven times over 19 days of experiment with either a saline solution (control) or an acetamiprid-saline solution, and sperm samples were retrieved before and after the experiment. The overall dose given to the birds corresponded to 0.5% of the LD50 for the Zebra finch (5.7 mg/kg BW) spread into 7 separate doses and administered every three days over the entire duration of the study (ca. 0.07% LD50 per oral dose). Sperm mobility and sperm oxidative status were unaffected by the treatment, but sperm density was. Birds that received oral doses of acetamiprid suffered a significant decline in their sperm density compared to control birds. This result was confirmed by a significant decrease in the activity of the antioxidant enzyme SOD in the sperm of acetamiprid-dosed birds. These results provide the first evidence of sublethal toxicity of acetamiprid in a songbird and suggest that passerine birds’ fertility may be negatively affected by very small doses of neonicotinoids in the wild. |
| Databáze: | OpenAIRE |
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