Outcome of Patients on Long Term Low-Density Lipoprotein Apheresis with Membrane Differential Filtration: A Case Study in Three Patients 14 Years on Treatment
| Autor: | Michael Schartl, A. Bimmermann, Hans von Baeyer |
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| Rok vydání: | 2000 |
| Předmět: |
Male
medicine.medical_specialty Time Factors Treatment interval Coronary Disease law.invention chemistry.chemical_compound Risk Factors law Internal medicine medicine Humans Myocardial infarction Low density lipoprotein apheresis Filtration Aged Cholesterol business.industry Cholesterol LDL General Medicine Middle Aged medicine.disease Coronary heart disease Surgery Lipoproteins LDL Treatment Outcome chemistry LDL apheresis Blood Component Removal Cardiology Hemofiltration business Follow-Up Studies Lipoprotein |
| Zdroj: | Therapeutic Apheresis. 4:386-394 |
| ISSN: | 1091-6660 |
| DOI: | 10.1046/j.1526-0968.2000.004005386.x |
| Popis: | Membrane differential filtration (MDF) (1,2) is a variety of cascade filtration. Three patients with primary hyperlipoproteinemia and coronary heart disease (2 patients with foregoing myocardial infarction) were treated with MDF for a period of 14 years. The mean treatment interval was 21 days. The basic level of low-density lipoprotein (LDL) cholesterol was about 450 mg/dl, and the level on LDL apheresis with comedication of statins was 180 to 200 mg/dl before treatment. Atherosclerosis progressed slowly during this period, and myocardial infarctions were avoided. However, in all 3 patients angiologic interventions became necessary. MDF is a well tolerated method that can be conducted without allergic hazards. The clinical results compare with those of other apheretic techniques. |
| Databáze: | OpenAIRE |
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