Devices for Noninvasive Transcranial Electrostimulation of the Brain Endorphinergic System: Application for Improvement of Human Psycho‐Physiological Status
Autor: | S.P. Kropotov, V.N. Sisoev, S.V. Rychkova, D.V. Glukhov, Gerald P. Kozlowski, Aleksandr Vyacheslavovich Malygin, E.M. Krupitski, L.I. Gerasimova, A.V. Kovalevski, Valery Pavlovich Lebedev |
---|---|
Rok vydání: | 2002 |
Předmět: |
Active placebo
medicine.medical_specialty Biomedical Engineering Medicine (miscellaneous) Electric Stimulation Therapy Bioengineering Audiology Biomaterials Animals Humans Medicine Heart rate variability Functional electrical stimulation Autonomic disturbances Mass disaster business.industry Brain food and beverages Equipment Design General Medicine Psychophysiologic Disorders Electric Stimulation Rats Posttraumatic stress Treatment Outcome Endorphins business Field conditions |
Zdroj: | Artificial Organs. 26:248-251 |
ISSN: | 1525-1594 0160-564X |
Popis: | It is well known that deficit of endorphins plays an important role in disturbances of human psycho-physiological status. Previously, we revealed that brain endorphinergic structures have quasiresonance characteristics. On the basis of these data, a method of activation of the brain endorphinergic structures by means of noninvasive and rather selective transcranial electrostimulation (TES) as a kind of functional electrical stimulation (FES) was elaborated. New models of TES devices (TRANSAIR) were developed for indoor and outdoor usage. To increase the efficacy of TES, the frequency modulation according to normal distribution in the limits of the quasiresonance characteristics was put into operation. The blind and placebo-controlled (passive and active placebo) study was produced to estimate the TES effects on stress events and accompanied psycho-physiological and autonomic disturbances of different intensities on volunteers and patients in the following groups: everyday stress and fatigue; stress in regular military service and in field conditions; stress in the relatives of those lost in mass disaster; posttraumatic stress (thermal burns); and affective disorders in a postabstinence period. Some subjective verbal and nonverbal tests and objective tests (including heart rate variability) were used for estimation of the initial level of psycho-physiological status, which changes after TES sessions. It was demonstrated that fatigue, stress, and other accompanied psycho-physiological disturbances were significantly improved or abolished after 2-5 TES sessions. The TES effects were more pronounced in cases of heavier disturbances. In conclusion, activation of the brain endorphinergic structures by TES is an effective homeostatic method of FES that sufficiently improves quality of life. |
Databáze: | OpenAIRE |
Externí odkaz: |