Bone mineral density of the lumbar spine in women with endometriosis
| Autor: | Nancy E Lane, Eric S. Orwoll, Joyce Baptista |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Adult
medicine.medical_specialty Endometriosis Normal values Bone Density medicine Humans Nafarelin Bone mineral Estradiol business.industry Body Weight Lumbosacral Region Obstetrics and Gynecology Middle Aged medicine.disease Spine Surgery Trabecular bone Diverse population Mineral density Reproductive Medicine Calcium Female Lumbar spine business Nuclear medicine medicine.drug |
| Zdroj: | Fertility and Sterility. 55:537-542 |
| ISSN: | 0015-0282 |
| DOI: | 10.1016/s0015-0282(16)54181-8 |
| Popis: | Young women with endometriosis have reduced cortical and trabecular bone mineral density of the wrist compared with age-matched controls. This conclusion was based on 41 subjects from one geographical location. The purpose of this study was to test this finding in a larger, more geographically diverse population. One hundred women with laparoscopically proven endometriosis were enrolled in this study for the evaluation of the efficacy of nafarelin, a gonadotropin-releasing hormone agonist. Patients were recruited from nine investigators across the United States and Canada, and bone mineral density of the lumbar spine was obtained at baseline, with 6 Hologic QDR (Hologic Inc., Waltham, MA) and a Lunar DPX (Lunar Radiation Corp., Madison, WI) instrument. The age of the women was 30.3 +/- 5.8 years (mean +/- SD); 91% were white. Bone mineral density of the lumbar spine was 1.1 +/- 0.11 g/cm2 (n = 85 Hologic QDR) and 1.2 +/- 0.93 g/cm2 (n = 15 Lunar DPX). Hologic bone mineral density was 104.8 +/- 11.0 and Lunar bone mineral density was 103.4% +/- 7.8% of normal values for age. To conclude, in a population based cross-sectional study of patients with endometriosis, we do not observe low bone mineral density of the lumbar spine by techniques that measure a combination of cortical and trabecular bone. |
| Databáze: | OpenAIRE |
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