Oncotherapeutic Application of Resveratrol-based Inorganic Nanoparticles
| Autor: | Muddasarul Hoda, Angela Perris, Junaid Jibran Jawed, Sanchari Bhattacharya |
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| Rok vydání: | 2021 |
| Předmět: |
Drug
business.industry Mechanism (biology) media_common.quotation_subject Phytochemicals Biomedical Engineering Metal Nanoparticles Pharmaceutical Science Cancer Resveratrol Pharmacology medicine.disease chemistry.chemical_compound chemistry In vivo Neoplasms Drug delivery Humans Medicine business Metal nanoparticles Inorganic nanoparticles media_common |
| Zdroj: | Pharmaceutical Nanotechnology. 9:271-280 |
| ISSN: | 2211-7385 |
| Popis: | Background: Potential therapeutic benefits of natural phytoconstituents and the emergence of nano-structured drug delivery systems have expanded the scope of enhanced chemotherapy with minimal adverse effects. Various in vivo and in vitro studies have revealed Resveratrol to be a potent anti-carcinogenic agent. Researchers are currently applying the concept of nano-science for enhancing the delivery of phyto-drugs like resveratrol, in order to carry the drug to the affected tissues and organs of cancer patients with much ease and efficiency. Methods: The current review emphasizes the use of inorganic nanoparticles for enhancing the delivery and efficacy of resveratrol into otherwise inaccessible tumorigenic tissues. Conclusion: The present review work summarizes a comprehensive update on the mechanism of actions of the resveratrol-based inorganic nanocomposite particles that are currently being studied against various cancer models. This work may be significant in laying the foundation for the future of metallic nanoparticles-based delivery and efficacy of phytochemicals in general and resveratrol in specific against non-invasive metastatic cancer. |
| Databáze: | OpenAIRE |
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