Development of a 3 French Dual-Frequency Intravascular Ultrasound Catheter
Autor: | Emmanuel Cherin, David E. Goertz, Isaac Jourard, Jill J. Weyers, F. Stuart Foster, Chelsea E. Munding, Brian K. Courtney |
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Rok vydání: | 2018 |
Předmět: |
medicine.medical_specialty
Catheters Acoustics and Ultrasonics Transducers Biophysics 030204 cardiovascular system & hematology 01 natural sciences 03 medical and health sciences 0302 clinical medicine 0103 physical sciences Intravascular ultrasound medicine Humans Dual frequency Radiology Nuclear Medicine and imaging 010301 acoustics Ultrasonography Interventional Radiological and Ultrasound Technology medicine.diagnostic_test Phantoms Imaging business.industry Fibrous cap Plaque rupture Equipment Design Coronary Vessels Plaque Atherosclerotic Catheter medicine.anatomical_structure Thin-cap fibroatheroma Transducer Radiology business Artery |
Zdroj: | Ultrasound in Medicine & Biology. 44:251-266 |
ISSN: | 0301-5629 |
Popis: | Coronary plaque morphology, including plaque size and fibrous cap thickness, is thought to contribute to the risk of plaque rupture and future cardiac events. Dual-frequency intravascular ultrasound has been proposed as a possible technique to visualize both large-scale features and superficial detail of coronary plaque; however, it has not been found to be feasible within the constraints of a clinically functional intravascular ultrasound catheter. In this study, we describe the design and fabrication of a dual-frequency catheter using a bidirectional transducer stack with center frequencies of approximately 30 and 80 MHz. We describe how the high-frequency transducer achieves significantly improved axial and lateral resolution (16 and 120 µm, respectively, vs. 50 and 220 µm) at the expense of penetration depth. Finally, imaging of ex vivo human coronary artery segments reveals that the catheter can provide complementary images of the deeper arterial wall and superficial plaque features. |
Databáze: | OpenAIRE |
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