Comparison of prognostic scales for patients with metastatic spine disease
| Autor: | Anton A. Denisov, Nikita S Zaborovsky, Dmitry A Mikhailov, Sergey V. Masevnin, Dmitry Ptashnikov, Oleg Smekalenkov |
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| Rok vydání: | 2020 |
| Předmět: |
Orthopedic surgery
medicine.medical_specialty Metastatic lesions Spinal tumors metastasis Tomita scale Tokuhashi scale Katagiri scale business.industry Neurological status Retrospective cohort study Disease medicine.disease Article Metastasis Spinal decompression medicine Orthopedics and Sports Medicine In patient Radiology business Survival rate RD701-811 |
| Zdroj: | Orthopedic Reviews, Vol 12, Iss 4 (2021) Orthopedic Reviews |
| ISSN: | 2035-8237 |
| Popis: | This is one-centre retrospective study with the aim to identify the scale, which provides the most accurate prediction of life expectancy in patients with metastatic lesions in spine. A retrospective analysis of clinical data of 138 patients with metastatic spinal tumors. Patients underwent spinal cord decompression and instrumented stabilization of affected area. We evaluated the general condition according to the Karnofsky and ECOG scales, the presence of metastases in the visceral organs, spine and other bones, the neurological status and conduction of the medical therapy before spinal surgery. Observed clinical parameters were converted to Tokuhashi, Tomita, and Katagiri scales. For statistical analysis, software environment R 3.4.1 was used. Assessment of prognostic accuracy was performed using ROC analysis. The Tokuhashi scale showed AUC 0.605 (95% CI 0.586-0.616), Tomita scale showed AUC 0.708 (95% CI 0.573-0.842), Katagiri scale showed AUC 0.650 (95% CI 0.508-0.792). The best results for survival rate predicting after surgical treatment for metastatic spinal lesions were shown the Tomita scale. |
| Databáze: | OpenAIRE |
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