Improvement Trajectories in Patient Reported Outcomes Differ Between Males and Females Following Anterior Cruciate Ligament Reconstruction

Autor: Elizabeth, Bjornsen, Caroline, Lisee, Todd A, Schwartz, Robert, Creighton, Ganesh, Kamath, Jeffrey, Spang, Troy, Blackburn, Brian, Pietrosimone
Rok vydání: 2022
Předmět:
Zdroj: Journal of Athletic Training.
ISSN: 1938-162X
1062-6050
Popis: CONTEXT Patient reported outcomes (PROs) are utilized to track recovery and inform clinical decision-making following anterior cruciate ligament reconstruction (ACLR). It remains unclear if sex influences the trajectory of improvements in PROs over time post-ACLR. OBJECTIVE 1) to examine the effect of sex on the association between months post-ACLR and Knee Osteoarthritis Outcome Scores (KOOS) Quality of Life (QOL) scores in individuals with ACLR; and 2) to assess sex differences in KOOS QOL at selected timepoints post-ACLR. DESIGN Cross-sectional SETTING Laboratory PATIENTS OR OTHER PARTICIPANTS 133 females (20±3 yrs) and 85 males (22±4 yrs) within 6–60 months of primary, unilateral ACLR. MAIN OUTCOME MEASURES KOOS QOL was completed at a single follow-up timepoint post-ACLR. A multivariate, linear regression model was utilized to assess the interaction of sex on the association between months post-ACLR and KOOS QOL. Sex-specific, linear regression models were then used to predict KOOS QOL estimated marginal means (EMM) at each clinical timepoint (6,12, 24, 36, 48 and 60 months post-ACLR) and compared between sex. RESULTS In the primary model (R2=0.16, p CONCLUSION Males appear to exhibit PROs improvement post-ACLR at increasing months post-ACLR, while females do not demonstrate the same magnitude of linear increase in KOOS QOL. Females may require extended intervention to improve clinical outcomes post-ACLR and address a plateau in QOL.
Databáze: OpenAIRE