Assessing the Metabolic Impact of Ground Chia Seed in Overweight and Obese Prepubescent Children: Results of a Double-Blind Randomized Clinical Trial
| Autor: | Paulo Cesar Pires Rosa, Marcos N. Eberlin, Fabíola Isabel Suano de Souza, Márcia Cristina Fernandes Messias, Guilherme Henrique Fagundes da Silva, Camila Saran da Silva, Roseli Oselka Sacardo Sarni, Rosana M. Alberici, Camila Ribeiro de Arruda Monteiro, Patrícia de Oliveira Carvalho, Ildenize B. S. Cunha, David Feder, Fernando Luiz Affonso Fonseca |
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| Rok vydání: | 2020 |
| Předmět: |
Male
0301 basic medicine medicine.medical_specialty medicine.medical_treatment Medicine (miscellaneous) Context (language use) Overweight Fibrinogen Childhood obesity law.invention 03 medical and health sciences 0302 clinical medicine Double-Blind Method Randomized controlled trial law Internal medicine medicine Humans Obesity Salvia Child 030109 nutrition & dietetics Nutrition and Dietetics Tumor Necrosis Factor-alpha business.industry Vitamin E Public health NF-kappa B medicine.disease Clinical trial Child Preschool 030220 oncology & carcinogenesis Seeds Female medicine.symptom business medicine.drug |
| Zdroj: | Journal of Medicinal Food. 23:224-232 |
| ISSN: | 1557-7600 1096-620X |
| DOI: | 10.1089/jmf.2019.0055 |
| Popis: | Childhood obesity is a medical condition of major public health concern. Chia seeds are used to treat certain noncommunicable diseases, and they are rich in omega-3 fatty acids, which contribute to the absorption of vitamins. A randomized double-blind clinical trial of 30 obese children was performed. The sample was composed of prepubertal 5- to 10-year-old children of both sexes with body mass indexes equal to or above the 95th percentile who were recruited through the Pediatric Department of the Faculdade de Medicina do ABC. Blood samples were drawn, the children were weighed and measured, and a 24-h dietary recall was obtained before and after the treatment. Not only were significant differences observed for fibrinogen (P = .011) but a correlation between the changes in markers and the presence of fibers was also observed for two inflammatory parameters: tumor necrosis factor-α (P = .027) and nuclear factor-κβ (P = .059). These results indicate that chia seeds may have anti-inflammatory effects related to their fiber content in the context of childhood obesity. |
| Databáze: | OpenAIRE |
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