Interval to delivery in high-risk patients: do tocolytic agents really work?
| Autor: | C.S. Bale, J.R. Allbert, R. C. Floyd, C.H. Lou, John C. Morrison, Kathy S. Gookin |
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| Rok vydání: | 1992 |
| Předmět: |
Adult
Tocolytic agent Uterine activity High risk patients Time Factors Preterm labor business.industry Obstetrics and Gynecology Gestational Age General Medicine Uterine Contraction Obstetric Labor Premature Tocolytic Agents Treatment Outcome Pregnancy Anesthesia Tocolytic Medicine Gestation Humans Labor Onset In patient Tocolytic Therapy Female business |
| Zdroj: | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics. 38(3) |
| ISSN: | 0020-7292 |
| Popis: | Some question whether tocolytic drugs reduce uterine activity and prolong gestation. The interval from discontinuance of tocolytics until spontaneous labor and delivery in patients (n = 69) with documented preterm labor (PTL) versus subjects receiving prophylactic tocolytic therapy (n = 41) was studied. Women with documented PTL delivered sooner after cessation of tocolytics (6.1 +/- 6.9 days) than control (C) patients (14.7 +/- 10.8 days, P less than 0.001). Also, 28 of the 69 (41%) patients in the PTL group delivered within 24 h of discontinuation of tocolysis compared to 4 (10%) in the C group (P less than 0.0004). We conclude that tocolytic therapy for documented preterm labor suppresses uterine activity and when these agents are discontinued, contractions return and labor ensues. |
| Databáze: | OpenAIRE |
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