Investigation of beta-lactam antibiotic-induced vancomycin-resistant MRSA (BIVR)
| Autor: | Hideaki Hanaki, Yoshio Yamaguchi, Chie Yanagisawa, Kazuaki Uehara, Hidehito Matsui, Yukie Yamaguchi, Yasuko Hososaka, Kazunari Barada, Fumiko Sakai, Keisuke Sunakawa, Yasuko Itabashi, Koichiro Atsuda, Shinsuke Ikeda, Haruo Tanaka, Takashi Inamatsu, Ariaki Nagayama |
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| Rok vydání: | 2004 |
| Předmět: |
Microbiology (medical)
medicine.medical_specialty Staphylococcus aureus medicine.drug_class Antibiotics Microbial Sensitivity Tests medicine.disease_cause beta-Lactams Microbiology chemistry.chemical_compound Medical microbiology Vancomycin resistant Medicine Pharmacology (medical) business.industry Vancomycin Resistance biochemical phenomena metabolism and nutrition Anti-Bacterial Agents Infectious Diseases chemistry Lactam Vancomycin Methicillin Resistance Peptidoglycan Detection rate business medicine.drug |
| Zdroj: | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 11(2) |
| ISSN: | 1341-321X |
| Popis: | We could not detect hetero-vancomycin-intermediate resistant Staphylococcus aureus (hetero-VISA), according to the definition of hetero-VISA, from the clinical isolates of 140 methicillin-resistant S. aureus (MRSA) strains. However, 15 beta-lactam antibiotic-induced vancomycin-resistant MRSA (BIVR) strains were detected from the same strains. We screened 1882 MRSA clinical isolates obtained in 2002 from 21 institutes throughout Japan. The detection rate of blood-isolated BIVR was 12.6% (19/151), and that of nonblood-isolated BIVR was 4.9% (85/1731; P0.001; chi2 test). Uridine-diphosphate-N-acetylmuramyl-L: -alanyl-D: -isoglutamyl-L: -lysine, used as the peptidoglycan material of S. aureus, showed the same results as beta-lactam antibiotics in BIVR. |
| Databáze: | OpenAIRE |
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