Metastatic Pleomorphic Lobular Carcinoma of the Breast to the Hypothalamus Presenting as a Primary Pituitary Lesion Presenting 17 Years Later-Report of a Case and Review of the Literature

Autor:	Seena C. Aisner, Leroy Sharer, James K. Liu, Ada Baisre de Leon, Debra S Heller
Rok vydání:	2022
Předmět:	Diagnosis Differential Carcinoma Lobular Hypothalamus Humans Breast Neoplasms Female Surgery Breast Anatomy skin and connective tissue diseases Pathology and Forensic Medicine
Zdroj:	International Journal of Surgical Pathology. 30:789-791
ISSN:	1940-2465 1066-8969
Popis:	Carcinomas metastatic to the brain are common, however, metastatic disease to the hypothalamic- pituitary region is uncommon and account for less than 3.6% of all resected malignant pituitary tumors. Most metastatic disease in that region derives from a lung or breast primary, with both ductal and lobular carcinoma reported. We report what we believe is the first case of pleomorphic lobular carcinoma metastatic to the hypothalamus. This case is also reaffirms that late metastasis from breast cancer should be considered in the differential diagnosis. It is important for the clinician to consider the clinical history of breast cancer, even when remote, in the differential diagnosis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d79784f01ce137364b1a03e60950d97 https://doi.org/10.1177/10668969221081739 Zobrazit plný text záznamu