Antimelanoma effect of manool in 2D cell cultures and reconstructed human skin models

Autor:	Heloiza D. Nicolella, Arthur B. Ribeiro, Carla Carolina Munari, Matheus R. Melo, Saulo D. Ozelin, Lucas Henrique D. da Silva, Franciane Marquele‐Oliveira, Renato P. Orenha, Rodrigo Cássio S. Veneziani, Renato Luis T. Parreira, Denise Crispim Tavares
Rok vydání:	2022
Předmět:	Health Toxicology and Mutagenesis Molecular Medicine General Medicine Toxicology Molecular Biology Biochemistry
Zdroj:	Journal of biochemical and molecular toxicologyREFERENCES.
ISSN:	1099-0461
Popis:	Melanoma is the most aggressive and lethal type of skin cancer, characterized by therapeutic resistance. In this context, the present study aimed to investigate the cytotoxic potential of manool, a diterpene from Salvia officinalis L., in human (A375) and murine (B16F10) melanoma cell lines. The analysis of cytotoxicity using the XTT assay showed the lowest IC
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d78abca2c04de65109458a6f19c5b2a https://pubmed.ncbi.nlm.nih.gov/36541366 Zobrazit plný text záznamu Plný text