Retrospective analysis of the association of nodular goiter with primary and secondary hyperparathyroidism
| Autor: | S Lastoria, L. dell’Erba, B Scarano, M Carletto, M Dondi, Calo-Gabrieli G, P Marinelli, A Ciampolillo, Giuliano Mariani, P Zagni, M Bagnasco, Massimo Santoro, Paola Anna Erba, N Borsato, P. Gerundini, G Bruno, S Baldari |
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| Přispěvatelé: | Dell'Erba, L, Baldari, S, Borsato, N, Bruno, G, Calò-Gabrieli, G, Carletto, M, Ciampolillo, A, Dondi, M, Erba, P, Gerundini, P, Lastoria, S, Marinelli, P, Santoro, M, Scarano, B, Zagni, P, Bagnasco, M, Mariani, G |
| Rok vydání: | 2001 |
| Předmět: |
Adult
Male medicine.medical_specialty Goiter Adolescent Endocrinology Diabetes and Metabolism Population Endocrinology Thyroid goiter hyperparathyroidism association Age Distribution Internal medicine medicine Prevalence Humans Risk factor Sex Distribution education Retrospective Studies education.field_of_study Hyperparathyroidism business.industry Thyroid disease Thyroid Retrospective cohort study General Medicine Middle Aged medicine.disease medicine.anatomical_structure Italy Secondary hyperparathyroidism Female Hyperparathyroidism Secondary business Goiter Nodular |
| Zdroj: | European journal of endocrinology. 145(4) |
| ISSN: | 0804-4643 |
| Popis: | BACKGROUND: The association of hyperparathyroidism (HPT) with thyroid disease has long been known, but the mechanisms underlying such an association have not yet been clarified. OBJECTIVE: To elucidate the main factors determining this combination of endocrine diseases, in a retrospective multicenter study. METHODS: We retrospectively reviewed all patients referred for parathyroid scintigraphy in the period 1990-1999. A total of 487 patients in the age range 17-65 years were selected for the analysis (339 women and 148 men); group A included 241 patients with primary and group B 246 patients with secondary HPT. RESULTS: A total of 124/241 patients in group A (51.5%), but only 92/246 patients in group B (38.2%) had thyroid disorders (notably nodular goiter) associated with HPT (P=0.0035). Thyroid disorders were evenly distributed throughout the entire 17-65 years age range in group A, but 17-40-year-old patients in group B had significantly fewer thyroid disorders than the older patients of the same group (15.5% compared with 43.3%, P |
| Databáze: | OpenAIRE |
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