Nocturnal Hypoventilation May Have a Protective Effect on Ischemic Heart Disease in Patients with Obesity Hypoventilation Syndrome
| Autor: | Giorgio Castellana, Silvano Dragonieri, Pierluigi Carratù, Lorenzo Marra, Vitaliano Nicola Quaranta, Teresa Ranieri, Onofrio Resta |
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| Rok vydání: | 2019 |
| Předmět: |
Male
0301 basic medicine Aging medicine.medical_specialty Myocardial Ischemia Nocturnal hypoventilation Comorbidity Disease Body Mass Index 03 medical and health sciences 0302 clinical medicine Internal medicine Obesity Hypoventilation Syndrome medicine Humans In patient Retrospective Studies Obesity hypoventilation syndrome Sleep Apnea Obstructive business.industry Sleep apnea Hypoventilation Middle Aged medicine.disease Respiratory Function Tests 030104 developmental biology Cardiology Female Geriatrics and Gerontology Ischemic heart business 030217 neurology & neurosurgery |
| Zdroj: | Rejuvenation Research. 22:13-19 |
| ISSN: | 1557-8577 1549-1684 |
| DOI: | 10.1089/rej.2017.2030 |
| Popis: | The importance of nocturnal hypoventilation (nHyp) in the development of cardiovascular comorbidity (CVM) in patients with obesity hypoventilation syndrome (OHS) is controversial. We recently hypothesized that nHyp may have a protective effect on CVM in OHS. The aim of this study was to evaluate the link between nHyp and CVM in patients with OHS. We performed a retrospective analysis of the clinical records of 60 patients with OHS. The initial population was divided into two groups: (1) 31 subjects with OHS and nHyp (nhOHS); (2) 29 individuals with OHS without nHyp (wnhOHS). All patients had also obstructive sleep apnea. Anthropometric data, medical history, electrocardiogram, pulmonary function testing, arterial blood gas test, and sleep recordings were collected. Patients with nhOHS, compared with those wnhOHS, showed higher values of PaCO |
| Databáze: | OpenAIRE |
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