When is a post-mortem skeletal survey of the fetus indicated, and when not?
Autor: | Desiree H. J. L. M. Koopmanschap, Carlo Marcelis, Willemijn M. Klein, Karin Kamphuis van Ulzen, John M. G. van Vugt |
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Rok vydání: | 2016 |
Předmět: |
Male
Pediatrics medicine.medical_specialty Skeletal survey Birth trauma 030218 nuclear medicine & medical imaging 03 medical and health sciences Fetus 0302 clinical medicine Pathognomonic medicine Humans 030212 general & internal medicine Skeleton Retrospective Studies business.industry Other Research Radboud Institute for Health Sciences [Radboudumc 0] Infant Newborn Obstetrics and Gynecology University hospital medicine.disease Radiography Pediatrics Perinatology and Child Health Female Autopsy business Rare cancers Radboud Institute for Health Sciences [Radboudumc 9] |
Zdroj: | Journal of Maternal-Fetal & Neonatal Medicine, 29, 6, pp. 991-7 Journal of Maternal-Fetal & Neonatal Medicine, 29, 991-7 |
ISSN: | 1476-7058 |
Popis: | Radiography after fetal or perinatal death has become a routine part of post-mortem diagnostics. However, only a selected subset of these babygrams or fetal post-mortem skeletal surveys (FPSSs) provides useful information. We investigated the indication for a FPSS.Inclusion consisted of the routinely made FPSS (2002-2012) in our university hospital in cases of fetal or perinatal death up to 7 days after birth. We categorized the diagnostic value of the FPSS as no, minor, major or pathognomonic. Regression analysis was used to determine the selection criteria for a useful FPSS.Three hundred and thirty-seven FPSS were included. Three hundred and five (91%) FPSS showed no or minor skeletal malformations. Fourteen (4.2%) FPSS had major skeletal malformations. In 18 (5.3%) cases the diagnosis was based on the pathognomonic skeletal malformations on the FPSS. Two cases were false positive after major birth trauma. The presence of multiple skeletal malformations on prenatal ultrasound or at post-mortem external inspection was highly indicative of a diagnostic FPSS (p0.001).The majority of the babygrams/FPSS has no contribution to the diagnostic process. Multiple skeletal malformations on prenatal ultrasound or post-mortem external inspection are indicative for a diagnostic FPSS, and this should be the main selection criterion. |
Databáze: | OpenAIRE |
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