Risk factors for developing dementia in type 2 diabetes mellitus patients with mild cognitive impairment
| Autor: | Oana Albai, Bogdan Timar, Romulus Timar, Mirela Frandes, Deiana Roman |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Pediatrics
medicine.medical_specialty Neuropsychiatric Disease and Treatment metabolic syndrome 03 medical and health sciences 0302 clinical medicine Insulin resistance Diabetes mellitus insulin resistance mental disorders Medicine Dementia Stroke Glycemic Original Research cognitive impairment business.industry Type 2 Diabetes Mellitus Cognition medicine.disease 030227 psychiatry diabetes mellitus Metabolic syndrome business 030217 neurology & neurosurgery dementia |
| Zdroj: | Neuropsychiatric Disease and Treatment |
| ISSN: | 1178-2021 1176-6328 |
| Popis: | Oana Albai,1 Mirela Frandes,2 Romulus Timar,1 Deiana Roman,3 Bogdan Timar2 1Second Department of Internal Medicine, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania; 2Department of Functional Sciences, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania; 3Municipal Clinical Emergency Hospital, Timisoara, Romania Background: Dementia and cognitive dysfunction have many causes. There is strong evidence that diabetes mellitus (DM) increases the risk of cognitive impairment and dementia. Optimal glycemic control, identification of diabetic risk factors, and prophylactic approach are essential in the prevention of cognitive complications.Aims: The main purpose of this study was to establish the cognitive impairment in DM patients, cared for in the Diabetes Center from Timisoara. Also, we investigated the prevalence of dementia in our group as well as the risk factors involved in the progression of mild cognitive impairment (MCI) to dementia.Patients and methods: We considered a sample of 207 type 2 DM (T2DM) patients, aged between 33 and 81 years, mean 57.49 (±11.37) years. We established the diagnosis of dementia based on the Mini-Mental State Examination (MMSE) test, as well as on the psychological testing, psychiatric and neurological investigations, and imaging tests (computerized tomography and MRI).Results: A percentage of 42.03% of patients presented MCI, mean age 63 (57.00–71.00) years, being older than patients without MCI, mean age 52.00 (45.00–61.00) years, P |
| Databáze: | OpenAIRE |
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