Varicella zoster and Borrelia burgdorferi are the main agents associated with facial paresis, especially in children
| Autor: | Seppo Sarna, Ilkka Seppälä, Sari Jäämaa, Matteus J. H. Salonen, Heli Piiparinen, Marjaleena Koskiniemi |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Adult
Male medicine.medical_specialty Mycoplasma pneumoniae Herpesvirus 3 Human Adolescent Facial Paralysis medicine.disease_cause Antibodies Viral 03 medical and health sciences 0302 clinical medicine Virology Internal medicine Medicine Humans 030212 general & internal medicine Borrelia burgdorferi 030223 otorhinolaryngology Child Paresis Aged Aged 80 and over Chlamydia biology business.industry Varicella zoster virus Chlamydophila pneumoniae Middle Aged biology.organism_classification medicine.disease Antibodies Bacterial Facial paralysis 3. Good health Infectious Diseases Child Preschool Immunology DNA Viral Etiology Female medicine.symptom business |
| Zdroj: | University of Helsinki |
| ISSN: | 1386-6532 |
| Popis: | Background: The etiology of facial paresis (FP) often remains unresolved. Yet, a microbial association is frequently suspected. Objective: To evaluate the infectious etiology of FP by using sensitive tests. Study design: We studied the serum and cerebrospinal fluid of 42 patients diagnosed with idiopathic peripheral facial paresis using sensitive serological methods and nucleic acid detection and for reference, 42 patients with other neurological disorders (OND) matched for age, sex, season and geographical area. Results: Varicella zoster virus and Borrelia burgdorferi accounted for 56% of all associated agents in children with FP compared with 11% of OND (P/0.01). In adults, the respective numbers were 29 and 13%. Other treatable etiological agents, Chlamydia pneumoniae and Mycoplasma pneumoniae , accounted for 11% in children and 8% in adults and with the same prevalence between patients with FP and OND. Conclusions: Microbes, with specific therapy available accounted for 52% of all associated agents in the patients with FP when compared with 26% in controls with OND (P/0.04). Based on this, we conclude that the patients with FP may benefit from antimicrobial therapy. # 2002 Elsevier Science B.V. All rights reserved. |
| Databáze: | OpenAIRE |
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