Fibroblast Activation Protein Inhibitor Imaging and Therapy in a Patient With Multiple Endocrine Neoplasia Type 2A Syndrome
| Autor: | Somaye, Barashki, Ghasemali, Divband, Emran, Askari, Hamidreza, Amini, Kamran, Aryana |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Clinical Nuclear Medicine. 47:e284-e286 |
| ISSN: | 1536-0229 0363-9762 |
| Popis: | A patient with multiple endocrine neoplasia type 2A syndrome who had exhausted several surgeries and radiotherapy was referred to nuclear medicine department for theranostic approaches. [68Ga]-DOTATATE PET/CT and [131I]I-mIBG SPECT/CT were performed, but the degree of uptake was insufficient for using the treatment companion of these tracers. Finally, 1 year later, [68Ga]-FAPI-46 PET/CT showed progressive disease with metastases to the lung, liver, bone, and lymph nodes with intense [68Ga]-FAPI-46 uptake. Treatment with [177Lu]Lu-FAPI-46 was done, and the patient tolerated treatment and showed evidence of clinical improvement following therapy. |
| Databáze: | OpenAIRE |
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