Hepatitis E in Long-Term Travelers from the Netherlands to Subtropical and Tropical Countries, 2008–2011
| Autor: | Gerrit Koen, Floortje Elfrink, Janke Schinkel, Femke W. Overbosch, Gerard J.B. Sonder |
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| Přispěvatelé: | AII - Infectious diseases, Graduate School, APH - Global Health, Medical Microbiology and Infection Prevention |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male Microbiology (medical) Time Factors Epidemiology viruses 030231 tropical medicine Attack rate lcsh:Medicine hepatitis E virus medicine.disease_cause History 21st Century lcsh:Infectious and parasitic diseases Young Adult 03 medical and health sciences 0302 clinical medicine Hepatitis E virus Risk Factors Seroepidemiologic Studies Environmental health medicine Humans Public Health Surveillance lcsh:RC109-216 030212 general & internal medicine Seroconversion Prospective cohort study travel long-term travelers Netherlands Tropical Climate business.industry Incidence Incidence (epidemiology) lcsh:R virus diseases Hepatitis E medicine.disease Infectious Diseases HEV Cohort Female hepatitis E Travel-Related Illness business Viral hepatitis |
| Zdroj: | Emerging Infectious Diseases, Vol 24, Iss 6, Pp 1055-1060 (2018) Emerging infectious diseases, 24(6), 1055-1060. Centers for Disease Control and Prevention (CDC) |
| ISSN: | 1080-6059 1080-6040 |
| Popis: | Hepatitis E virus (HEV) is a common cause of acute viral hepatitis. Virus genotypes 1 and 2 infect humans in developing countries by the fecal-oral route. To assess attack rates and disease incidence for travelers, we prospectively studied 604 long-term travelers to subtropical and tropical countries. Participants donated blood samples pretravel and posttravel and kept a diary. A total of 89/604 (15%) pretravel samples were positive for HEV IgG by ELISA, suggesting previous HEV infection. Seroconversion for HEV was found for 19/515 travelers (attack rate 3.7%, incidence 1.8 cases/1,000 person-weeks). We believe there is a substantial risk for acquiring HEV infection among long-term travelers. Although HEV infection does not seem to be a major problem in this healthy cohort, hygienic measures should be stressed in all pretravel health advice, particularly for pregnant women and immunocompromised travelers who are at risk for severe disease. |
| Databáze: | OpenAIRE |
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