| Autor: |
Ze-Le Chen, Claire Empel, Kun Wang, Pan-Pan Wu, Bao-Gui Cai, Lei Li, Rene M. Koenigs, Jun Xuan |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Organic letters. 24(11) |
| ISSN: |
1523-7052 |
| Popis: |
Herein we report a site-selective cyclopropanation of N-heterocyclic carbene (NHC)-borane complexes via photochemical carbene transfer reactions. By subtle changes to the reaction conditions, this approach can be further extended toward the difunctionalization of NHC-boranes via cyclopropanation and the B-H insertion reaction. Further investigations in photochemical continuous-flow applications and synthetic transformations proved the utility of the method. Theoretical calculations and control experiments were performed to explain the observed selectivity. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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