Physiologic benefits of exercise training in rehabilitation of patients with severe chronic obstructive pulmonary disease
| Autor: | Christopher B. Cooper, Mary R. Burns, Richard Casaburi, Eve Carithers, Robert S. Y. Chang, Janos Porszasz |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male medicine.medical_specialty Respiratory rate Physical exercise Critical Care and Intensive Care Medicine Oxygen Consumption Capnography Heart Rate Internal medicine Heart rate medicine Humans Lactic Acid Lung Diseases Obstructive Tidal volume Aged COPD business.industry Pulmonary Gas Exchange Training effect Middle Aged medicine.disease Exercise Therapy Breathing Cardiology Exercise intensity Physical therapy Exercise Test Respiratory Mechanics Female business |
| Zdroj: | American journal of respiratory and critical care medicine. 155(5) |
| ISSN: | 1073-449X |
| Popis: | We determined the effect on exercise tolerance and physiological exercise responses of rigorous rehabilitative exercise training in chronic obstructive pulmonary disease (COPD). Fifteen men and 10 women (mean age, 68 +/- 6 yr; FEV1, 0.93 +/- 0.27 L) participated in a rehabilitation program with an exercise component of three per week 45-min sessions of cycle ergometer training for 6 wk with exercise intensity kept near maximal targets. Before and after rehabilitation, patients performed an incremental test and a constant work rate (CWR) test at 80% of the peak work rate in the preprogram incremental test. Ventilation (V(E)) and gas exchange were measured breath by breath; arterialized venous blood was analyzed for blood gas determinations and lactate. Rehabilitation yielded an average increase in peak work rate in the incremental test of 36% (p < 0.001), and in the duration of the CWR test of 77% (p < 0.001). In the CWR test, the kinetics of O2 uptake, CO2 output, V(E), and heart rate were markedly slower than those of healthy subjects. After training, mean response time decrease averaged 17, 22, 34, and 29%, respectively (p < 0.02), evidence of a physiologic training effect. Further, for identical CWR tasks, V(E) was 10% lower (p < 0.02) after training, attributable to altered breathing pattern: tidal volume increased by 8% and respiratory rate decreased by 19%, yielding lower V(D) /V(T) (0.46 versus 0.53 p < 0.005). Rigorous exercise training for patients with severe COPD yields more efficient exercise breathing pattern and lower V(E); this is associated with improved exercise tolerance. |
| Databáze: | OpenAIRE |
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