Point of care influenza testing using Alere-i Influenza A & B assay: a practical assessment

Autor: Jessica Buckley, Timothy K. Blackmore, Michelle Balm, Karen Corban, Chor-Ee Tan, Matthew J. Kelly, James Taylor
Jazyk: angličtina
Rok vydání: 2018
Předmět:
DOI: 10.1101/375493
Popis: We assessed the utility of the Alere i Influenza A & B point of care influenza test (Ai-POCIT) with laboratory testing using RT-PCR. 270 adult hospital patients had both Ai-POCIT and laboratory influenza tests conducted on the same sample. Overall, 30% and 32% influenza tests were positive by Ai-POCIT and RT-PCR, respectively. The sensitivity of the Ai-POCIT for influenza A, influenza B and any influenza were 93%, 100%, and 95%, respectively. Specificity was 100% for both viruses, but an 11% test failure rate indicates the need for better training of users. We believe that the use of nasopharyngeal (NP) swabs resulted in the observed high performance of the Ai-POCIT in comparison to other published studies. Ai-POCIT was regarded as very useful by front line clinical staff for clinical decision making and acute bed management.
Databáze: OpenAIRE