Contribution of oral magnetic particles in MR imaging of the abdomen with spin-echo and gradient-echo sequences
| Autor: | Frank Boudghene, Jean-Didier Grange, Torre Bach-Gansmo, Christine Nantois, Claudy Wallays, Samuel Lame, J.-M. Bigot |
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| Rok vydání: | 1993 |
| Předmět: |
Male
medicine.medical_specialty Diagnostic information Iron Contrast Media Peritoneal Diseases Precontrast Abdomen medicine Humans Radiology Nuclear Medicine and imaging Retroperitoneal Space Magnetite Nanoparticles medicine.diagnostic_test business.industry Liver Diseases Dextrans Oxides Magnetic resonance imaging Middle Aged Image Enhancement Magnetic Resonance Imaging Mr imaging Ferrosoferric Oxide medicine.anatomical_structure Spin echo Magnetic nanoparticles Female Radiology Artifacts Nuclear medicine business Gradient echo |
| Zdroj: | Journal of Magnetic Resonance Imaging. 3:107-112 |
| ISSN: | 1522-2586 1053-1807 |
| DOI: | 10.1002/jmri.1880030118 |
| Popis: | An open phase III clinical trial of the oral contrast agent OMP (oral magnetic particles) was performed in 35 patients undergoing abdominal magnetic resonance (MR) imaging at 1.5 T with axial spin-echo and gradient-echo sequences. The diagnostic efficacy of OMP was examined by comparing pre- and postcontrast images. Bowel loops and abdominal organs were more easily recognizable after OMP ingestion, and the general quality of the images was improved because of fewer bowel-related artifacts. The diagnostic value of the postcontrast abdominal MR examination was superior or equal to that of the precontrast study, and additional information was obtained in 44% of the cases. Postcontrast gradient-echo sequences increased confidence in the MR examination in 18% of cases. OMP was well tolerated and increased the quality and amount of diagnostic information acquired during the examination. Gradient-echo imaging was found to be a useful complement, but the need for a reduction in susceptibility artifacts was apparent and indicates that a decrease in TE or the use of rapid spin-echo sequences might be advantageous. |
| Databáze: | OpenAIRE |
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