Splenectomy and spontaneous remission in children with chronic idiopathic thrombocytopenic purpura
| Autor: | María Cristina Rapetti, Hugo Donato, Armando Picón, Gabriel Schvartzman, Juan Jose Di Santo, Amadeo Rosso, Constanza Drozdowski |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
medicine.medical_specialty
Adolescent Databases Factual medicine.medical_treatment Treatment outcome Splenectomy Remission Spontaneous Spontaneous remission Gastroenterology FAVORABLE RESPONSE Recovery rate Internal medicine Outcome Assessment Health Care Medicine Humans Platelet Child Purpura Thrombocytopenic Idiopathic business.industry Platelet Count Remission Induction Chronic idiopathic thrombocytopenic purpura Age Factors Infant Hematology Surgery Purpura Treatment Outcome Oncology Child Preschool Pediatrics Perinatology and Child Health Chronic Disease medicine.symptom business Follow-Up Studies |
| Zdroj: | Pediatric bloodcancer. 47 |
| ISSN: | 1545-5009 |
| Popis: | Two hundred thirty of 696 evaluable children were identified as having chronic idiopathic thrombocytopenic purpura (ITP). Splenectomy was performed in 30 (13%), achieving remission in 22 (73%). Favorable response was associated to higher initial platelet count. Spontaneous remission was achieved by 53/200 non-splenectomized patients (26.5%), up to 10 years from diagnosis. More than half of them recovered between 6th and 12th month from diagnosis. The recovery rate was significantly higher (P=0.03) in children aged |
| Databáze: | OpenAIRE |
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