Renal biopsies performed before versus during ablation of T1 renal tumors
| Autor: | B.W. Lagerveld, Alexander D. Montauban van Swijndregt, Christiaan V. Widdershoven, Axel Bex, Warner Prevoo, Otto M. van Delden, Michaël M E L Henderickx, Elisabeth G. Klompenhouwer, Reindert J.A. van Moorselaar, Patricia J. Zondervan, B. M. Aarts |
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| Přispěvatelé: | RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, Graduate School, Urology, APH - Personalized Medicine, APH - Quality of Care, Radiology and Nuclear Medicine, ACS - Amsterdam Cardiovascular Sciences, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, CCA -Cancer Center Amsterdam, CCA - Imaging and biomarkers |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Radiofrequency ablation Urology medicine.medical_treatment Biopsy BENIGN 030232 urology & nephrology Medical Overuse Kidney 030218 nuclear medicine & medical imaging law.invention 03 medical and health sciences 0302 clinical medicine law Internal medicine Renal mass Medicine Humans Radiology Nuclear Medicine and imaging In patient RADIOFREQUENCY ABLATION Renal Carcinoma Renal Cell Retrospective Studies Renal mass biopsy COMPLICATIONS Radiological and Ultrasound Technology medicine.diagnostic_test business.industry PERCUTANEOUS ABLATION Gastroenterology Kidneys Ureters Bladder Retroperitoneum Hepatology Ablation Thermal ablation Kidney Neoplasms medicine.anatomical_structure Multicenter study MASS BIOPSY Radiology business Follow-Up Studies |
| Zdroj: | Abdominal Radiology (New York) Widdershoven, C V, Aarts, B M, Zondervan, P J, Henderickx, M M E L, Klompenhouwer, E G, van Delden, O M, Prevoo, W, Montauban van Swijndregt, A D, van Moorselaar, R J A, Bex, A & Lagerveld, B W 2021, ' Renal biopsies performed before versus during ablation of T1 renal tumors : implications for prevention of overtreatment and follow-up ', Abdominal Radiology, vol. 46, no. 1, pp. 373-379 . https://doi.org/10.1007/s00261-020-02613-4 Abdominal Radiology, 46(1), 373-379. Springer ABDOMINAL RADIOLOGY, 46(1), 373-379 Abdominal Radiology, 46(1), 373-379. Springer New York |
| ISSN: | 2366-004X |
| DOI: | 10.1007/s00261-020-02613-4 |
| Popis: | Purpose To assess the difference between renal mass biopsy (RMB) performed either before or during the ablation procedure. Methods A retrospective multicenter study was performed in patients with a cT1 renal mass treated with ablation between January 2007 and July 2019, including a search in the national pathology database for patients with a RMB planned for ablation. Patient and tumor characteristics and information on malignant, benign, and non-diagnostic biopsy results were collected to establish rates of overtreatment and number of ablations avoided in case of benign or non-diagnostic histology. Results RMB was performed in 714 patients, of which 231 patients received biopsy before planned ablation, and 483 patients at the time of ablation. Pathology results before ablation were malignant in 63% (145/231), benign in 20% (46/231) and non-diagnostic in 17% (40/231). Pathology results at the time of ablation were malignant in 67.5% (326/483), benign in 16.8% (81/483) and non-diagnostic in 15.7% (76/483), leading to a total of 32.5% of ablation of benign or non-diagnostic lesions. Of the patients with a benign biopsy obtained before ablation, 80.4% (37/46) chose not to undergo ablation. Patients with inconclusive biopsy before planned ablation chose an informed individualized approach including ablation, repeated biopsy, or no intervention in 56%, 34% and 10%. Conclusion This study emphasizes the importance of obtaining a biopsy prior to the ablation procedure in a separate session to lower the rate of potentially unnecessary ablations. |
| Databáze: | OpenAIRE |
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