Protection of DNA by metal ions at 95 °C: from lower critical solution temperature (LCST) behavior to coordination-driven self-assembly
| Autor: | Chang Lu, Yuancong Xu, Po-Jung Jimmy Huang, Mohamad Zandieh, Yihao Wang, Jinkai Zheng, Juewen Liu |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Nanoscale. 14:14613-14622 |
| ISSN: | 2040-3372 2040-3364 |
| DOI: | 10.1039/d2nr03461a |
| Popis: | While polyvalent metal ions and heating can both degrade nucleic acids, we herein report that a combination of them leads to stabilization. After incubating 4 mM various metal ions and DNA oligonucleotides at 95 °C for 3 h at pH 6 or 8, metal ions were divided into four groups based on gel electrophoresis results. Mg |
| Databáze: | OpenAIRE |
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