Efficacy of viable BCG vaccine paste in the treatment of common warts: a double-blind randomized control trial
| Autor: | Mehrnaz Soghrati, Nader Pazyar, Gholamreza Houshmand, Sedighe Tavakoli, Ali Abounoori, Mahdi Abounoori, Reza Yaghoobi |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Scars Dermatology law.invention Double blind 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Randomized controlled trial Double-Blind Method law medicine Humans Common warts 030203 arthritis & rheumatology Bacillus (shape) biology business.industry Remission Induction virus diseases Immunotherapy biology.organism_classification medicine.disease Treatment Outcome BCG Vaccine medicine.symptom Warts business BCG vaccine |
| Zdroj: | The Journal of dermatological treatment. 33(4) |
| ISSN: | 1471-1753 |
| Popis: | Treatment of common warts may be painful or leaves scars, mainly using traditional destructive methods. This study aimed to evaluate the efficacy of the viable Bacillus Calmette-Guérin (BCG) vaccine in paste formula as an immunotherapeutic modality for common warts treatment.This double-blind and randomized, parallel-group, placebo-controlled trial was conducted at the Ahvaz Imam Hospital Dermatology Department from November 2014 to 2015. Overall 80 patients with common warts in two groups (case and control) received BCG vaccine paste once weekly for eight consecutive weeks. Follow-up was done every two weeks during treatment and six months after the treatment to evaluate recurrence in patients with complete resolution.In group A, eight patients (20%) had a complete response, 15 patients (37.5%) partial response, four patients (10%) low response, and 13 patients (32.5%) no response (Topical BCG vaccine paste was an effective treatment for common warts, without recurrence and significant complications. |
| Databáze: | OpenAIRE |
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