Ischemia-modified albumin levels in children having seizure
| Autor: | Senay Haspolat, Sebahat Ozdem, Pinar Gencpinar, Anil Aktas Samur, Demet Orhan, Gulbahar Uzun, Asli Inci, Özgür Duman |
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| Rok vydání: | 2013 |
| Předmět: |
Male
medicine.medical_specialty Time Factors Neurology Serum Albumin Human Status epilepticus Seizures Febrile Epilepsy Developmental Neuroscience Predictive Value of Tests Seizures Convulsion medicine Humans Child Serum Albumin business.industry Seizure types Ischemia-modified albumin Significant difference Infant General Medicine Hypoxia (medical) medicine.disease Child Preschool Anesthesia Pediatrics Perinatology and Child Health Female Neurology (clinical) medicine.symptom business Biomarkers |
| Zdroj: | Brain and Development. 35:849-852 |
| ISSN: | 0387-7604 |
| DOI: | 10.1016/j.braindev.2012.11.004 |
| Popis: | Convulsions are one of the frequently seen problems for a neurologist in the daily routine. It is difficult to distinguish the seizure from pseudo-seizure because of lack of conclusive tests. The aim of this study is to investigate the relationship between seizure types and seizure periods by studying IMA serum levels in children having seizure. Two groups were included (patients and control) in our study. The patient group consisted of the children admitted to Pediatric Emergency Care during January 2008–January 2010 with seizure and the control group consisted of healthy children. Serum Ischemia modified albumin (IMA) level in the group having seizures was 99.7 and 83.2 U/ml in the control group. In the comparison of the patient and control groups, significant differences were found between their IMA values (p = 0.000). There was a significant difference between IMA values of the group having generalized tonic–clonic seizures and those of the control group (p = 0.001). In comparison of the IMA values of the group having febrile convulsions and those of the control group, a significant difference was determined (p = 0.011). It has been shown that if the seizure was prolonged over 5 min, IMA level increased, and there was a significant difference between the groups experiencing over 5 min of seizures and the groups experiencing less than 5 min of seizures (p = 0.001). An increase in IMA levels in febrile convulsion supports the hypoxia development in the brain during the seizure. Serum IMA levels increased with the elongation of the seizure period and may be an indicator for status epilepticus. 2012 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved. |
| Databáze: | OpenAIRE |
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